A romantic comedy exploring a week in the life of Jane (Louisa Krause), a young woman looking for love in New York City. Despite dealing with the everyday challenges of being on the autism spectrum, Jane looks to her older sister Bianca (Eliza Dushku), to help her find her very first boyfriend. As the innocent Jane embarks on new territory, and as Bianca worries that Jane's heart will be broken, they open up a new chapter in their relationship as sisters.